Reproduction Abstracts

Introduction: During the establishment of pregnancy, extravillous trophoblast (EVT) must invade through the decidua to form a functional placenta. Impaired decidualization is associated with placental insufficiency, including preeclampsia. The mechanisms by which decidual cells interact with EVT remain largely unknown. We hypothesised that decidual–EVT interactions are critical for appropriate invasion.Methods: Primary human endometrial stromal cell...